MOTS-c
For laboratory research only — not for human consumption. Sold and shipped by Peptide Plus, not Alphapeptide. Use code ALPHA10 at checkout. Alphapeptide earns a commission on referred sales.
How it’s studied.
A 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA. In research literature, MOTS-c is associated with AMPK pathway activation, glucose homeostasis, fatty-acid oxidation, and insulin sensitivity in metabolic studies. Translocates to the nucleus under metabolic stress to regulate adaptive gene expression.
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is one of the first identified mitochondrial-derived peptides. It is encoded within the mitochondrial genome rather than the nuclear genome, which makes it an unusual subject in research on mitochondrial-nuclear retrograde signaling and metabolic adaptation.
Half-life note · Short plasma half-life observed in animal studies.
Research areas.
- 01
AMPK pathway research
- 02
Metabolic homeostasis studies
- 03
Mitochondrial signaling research
- 04
Insulin sensitivity models
Reported in literature: 0.5–5 mg/kg in animal models (research only)
Pre-filled defaults for MOTS-c.
- Concentration
- 2.50mg/mL
- Draw on U-100
- 200units
- Volume / dose
- 2.000mL
- Doses / vial
- 1
Assumes 27-gauge insulin syringe, U-100 markings. Verify before use.
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